RB Burger is a hamburger chain that becomes the obsession of a killer in "Exquisite Corpses".
Francine, Roger and Jeff decide to go into business for themselves as tour guides, and when pressured by Stan, Hayley and Steve, choose the murder sites of the 'RB Killer' for their tours, so named for his habit of placing RB Burger bags over the heads of his victims. When their inaugural tour starts to go poorly, they grab some police band radios and are rewarded by a fresh murder. But when everyone re-boards the bus, they find they have an extra passenger in the form of the killer, who gives his name as Matthew. Torn between losing their review or saving the passengers, they allow the killer to lead them to a sewer where he reveals his kills are intended to bring back the Big Beef Blopper, a long-vanished temporary menu item. After nearly killing both Roger and Jeff, Francine manages to disarm him as the rest of the passengers get to live out their Dexter fantasy while taking out the killer as the trio slip away. Later, the news reports that due to the stoppage of murder victims, RB's is bringing back the Big Beef Blopper the killer desired.
Klaus, Steve and Principal Lewis visit RB Burger in "Silicon Steve."