Karen Shipley is a DJ for WLNG 98.2 radio.
In "The Wondercabinet", when radio show host Palmer Elymas goes missing from his show on new age mysticism, she fills in for him and notes that he hasn't returned any calls. Steve, a devotee of Palmer's show, suspects a conspiracy so he leads his friends to the radio station to locate Palmer's address to search for him. While leaving, Barry calls in a dedication for a cartoon bird car insurance mascot.
Karen is voiced by Rachael MacFarlane.