The First Episcopalian Church is where the Smith Family attend services. Father Donovan is the priest, often cutting services short to go fishing.
Stan becomes a church Deacon in "Deacon Stan, Jesus Man".
In "Rapture's Delight", Stan and Francine have sex in the janitor's closet and miss out on The Rapture.
Steve briefly sees the church while having an out-of-body experience in "The Wondercabinet".