- The title is a pun on Primum non nocere which means "First, do no harm." It is considered a guiding principle for doctors and physicians that they should take no action that could deliberately injure their patient.[1]
- After breaking down, Stan asks "Are you a good hillbilly, or a bad hillbilly?", paying homage to both Dorothy in The Wizard of Oz, as well as the film Deliverance.
- The painting of the farmer with the big pitchfork that Francine is referring to is American Gothic by Grant Wood.[2]
Previous Episode's References /// First, Do No Farm's References \\\ Next Episode's References
| << Season 14 | American Dad Season 15 | Season 16 >> | ||||||
| #01 | 100 Years a Solid Fool | #09 | Game Night | #16 | The Old Country | |||
| #02 | A Starboy is Born | #10 | American Data? | #17 | Businessly Brunette | |||
| #03 | Tapped Out | #11 | Salute Your Sllort | #18 | The Chilly Thrillies | |||
| #04 | Brave N00b World | #12 | Ghost Dad | #19 | Dammmm, Stan! | |||
| #05 | Into the Woods | #13 | Men II Boyz | #20 | The Last Ride of the Dodge City Rambler | |||
| #06 | One Fish, Two Fish | #14 | First, Do No Farm | #21 | 300 | |||
| #07 | Exquisite Corpses | #15 | Roger Needs Dick | #22 | Yule. Tide. Repeat. | |||
| #08 | Trophy Wife, Trophy Life |
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