Fatso was the protagonist in a video that became in internet meme of a cat playing an electronic keyboard under the title "charlie schmidt's cool cats" in June 2007. Fatso, who died in 1987, was owned and manipulated by Charlie Schmidt of Spokane, Washington.
When Stan takes the family to Peru to stay with a "lost tribe" in order to avoid his shame after being embarrassed by pooping in the neighbor's pool during a party in "An Incident at Owl Creek", he discovers that he isn't safe there either as they have access to the internet to see not only his accident video, but then watch Keyboard Cat.