Dalai Lama is a title given to spiritual leaders of the Tibetan people. They are part of the Gelug or "Yellow Hat" school of Tibetan Buddhism. The Dalai Lama title was created by Altan Khan, the Prince of Shunyi in 1578.
The 14th Dalai Lama, Tenzin Gyatso's picture appears on a poster of suspected lizard people in "Paranoid Frandroid".
The Dalai Lama appears at a meeting of religious leaders in "300", and is killed in a Mexican standoff.
The opening credits of Morning Mimosa show Suze wrestling with the Dalai Lama in "Gold Top Nuts".