Cheesers is a mouse that Stan uses to come to his rescue. He first appeared in "Live and Let Fry" when Stan gave him bad food when trans-fats were banned then promised that they would go out for ice cream later.

In "Stan's Night Out", when Dick insults a hooker named Misty by refusing to pay for sex, she steals his car which has three people locked in the truck which Stan had been trying to help throughout the evening and sells it to a crime lord, Fernando Jaramillo. When they are captured by Fernando and his men, Stan's first two escape plans involving Dick's dog Biscuit and Stan's mouse Cheesers backfire, forcing him to make a bet that he can start a lawnmower ten times on the first try based on a television show he had watched previously. Stan fails and Fernando prepares to cut off Stan's leg for winning the bet. When Stan appears at work the next day, it appears his leg is missing. But then Stan reveals he is still two-legged and reports Cheesers came back to his rescue.

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